This systematic review on predictors or moderators of treatment outcome across diagnoses in guided internet-based interventions (IBIs) for adults aimed to aggregate results of relevant studies. Better adherence, treatment credibility, and working alliance emerged as conclusive predictors/moderators for better outcome, whereas higher baseline scores predicted more reliable change but higher post-treatment symptoms. The review highlights that it is currently difficult to predict, across diagnoses, who will benefit from guided IBIs.
